In my last blog post, I described how Wasserstein (a.k.a. Earth-Mover’s) distances could be used to measure the dissimilarity between two neural response patterns. The main benefit of “Brain-Mover’s Distance” is that it takes the topology of the brain into account, measuring not just how similarly the voxels in question respond, but also their proximity in the brain. I also worked through an example to demonstrate how this method could be used to assess the replicability or inter-subject reliability of an fMRI dataset.